The Fatal Truth Behind Cytopoint Injections for Dogs

Cytopoint is often marketed as a "miracle" solution for dogs suffering from chronic itching, allergies, and skin conditions. Many veterinarians promote it as a safe and effective alternative to steroids or Apoquel. However, what pet parents aren’t told is the serious and even fatal risks associated with this injection. Cytopoint may provide temporary relief, but at what cost? Let’s uncover the truth behind this widely used drug.

1. What Is Cytopoint?

Cytopoint (lokivetmab) is an injectable monoclonal antibody therapy designed to target and neutralize Interleukin-31 (IL-31)—a protein involved in sending itch signals to the brain. Unlike traditional allergy medications that suppress the immune system, Cytopoint blocks the body's natural response to itching rather than addressing the root cause of allergies.
On the surface, this sounds like a safe approach. However, IL-31 plays a much larger role in immune regulation than just causing itching. Suppressing this key immune signal can have dangerous, long-term consequences.



2. The Hidden Dangers of Cytopoint

Many dog owners report severe reactions and tragic outcomes after their pets receive Cytopoint injections. These include:

A. Suppressed Immune Function
IL-31 isn’t just responsible for itchiness—it’s part of the body’s immune defense system. Blocking it can lead to:
• Increased susceptibility to infections (bacterial, viral, and fungal)
• Higher risk of cancer development due to unchecked cell growth
• Weakened response to disease
Some pet parents have reported their dogs developing autoimmune disorders, chronic infections, and even cancer after repeated Cytopoint use.

B. Neurological and Behavioral Side Effects
Cytopoint can interfere with normal nervous system function, leading to:
• Seizures or tremors
• Loss of coordination
• Lethargy and extreme fatigue
• Personality changes (aggression, anxiety, or depression)
In some cases, dogs who were once active and full of life became withdrawn, lethargic, or even experienced sudden neurological decline.

C. Organ Damage and Fatal Reactions
Some dogs have experienced acute liver and kidney failure after receiving Cytopoint injections. While drug companies claim these reactions are rare, many pet parents have lost their dogs shortly after an injection.
Signs of a serious reaction include:
• Vomiting or diarrhea
• Loss of appetite
• Jaundice (yellowing of the gums and eyes)
• Seizures or collapse
If your dog shows any of these symptoms after a Cytopoint injection, seek emergency veterinary care immediately.



3. Cytopoint Doesn't Address the Root Cause of Allergies

Like Apoquel and steroids, Cytopoint only masks symptoms instead of addressing the real cause of your dog’s allergies. Common underlying triggers include:
• Poor gut health and microbiome imbalance
• Processed, high-inflammatory diets (kibble, grains, and fillers)
• Toxin overload from vaccines, flea/tick preventatives, and environmental chemicals
• Leaky gut syndrome, leading to chronic inflammation
Instead of blocking your dog’s immune system with Cytopoint, it’s essential to focus on healing from the inside out.



4. Safer, Natural Alternatives to Cytopoint
Rather than relying on risky injections, try these natural solutions to support your dog’s immune system and reduce allergies:

A. Species-Appropriate Raw Diet
Feeding fresh, unprocessed food reduces inflammation and supports a healthy gut microbiome. Raw-fed dogs often see a dramatic improvement in allergy symptoms.

B. Gut Health Support
• Probiotics & Digestive Enzymes – Strengthen the immune system and reduce histamine reactions.
• Bone Broth & Colostrum – Help repair leaky gut and soothe inflammation.

C. Natural Antihistamines
• Quercetin ("Nature’s Benadryl") – Stabilizes mast cells and reduces itching.
• Bovine Colostrum – Helps balance the immune system and reduces allergic reactions.

D. Omega-3s and Anti-Inflammatory Supplements
• Green-lipped mussels
• Wild-caught sardines
• Turmeric (curcumin) for inflammation

E. Detox Pathways & Liver Support
• Milk thistle – Supports the liver in eliminating toxins.
• Chlorophyll & Spirulina – Help detox the body and reduce oxidative stress.



Final Thoughts: Is Cytopoint Worth the Risk?

While Cytopoint may offer temporary relief from itching, the potential dangers far outweigh the benefits. Blocking the immune system's natural processes can have devastating, long-term effects. Instead of using risky pharmaceutical interventions, a holistic approach focused on nutrition, gut health, and detoxification is the safest and most effective way to address allergies.
If your dog is struggling with allergies or chronic itching, contact me to create a safe, natural treatment plan that supports healing from the inside out.